Well, from last 3 weeks the world is fighting against the novel Sars2-Covid19 (better known as Coronavirus) disease. Is anti malarial drugs answer to this Coronavirus vaccine ? Lets check it out.
While US president Trump is advocating usage of two drugs namely chloroquine and hydroxychloroquine for treatment of Covid 19 but US FDA has still not approved these both drugs as treatment for the disease.
Both these drugs are useful for treatment for Malaria, lupus and rheumatoid arthritis. However these both are assessed for clinical trial before these can be declared as vaccine to Covid 19.
What are the components of these drugs?
Chloroquine is classified as antimalarials and ambecides drug. It is used to treat malaria. It is derived from the bark of Chinchona tree. The drug is now generic and relatively cheap. Aralane is the generic name of this medicine. There are mild side effects for this drug from diarrhea, loss of appetite to severe loss of vision and others. So please dont take this medicine without the prescription of registered medical practitioner.(Source – https://medlineplus.gov/druginfo/meds/a682318.html )
Hydroxychloroquine is similar drug to chloroquine but somewhat less toxic to it. It is used for prevention and treatment of malaria disease. Plaquenil is the generic name of this drug. This drug is well tolerated by most of the people. (source – https://www.medicinenet.com/script/main/art.asp?articlekey=229156 )
But Why this drug is said to be possible vaccine for Coronavirus?
This suggestion comes after the French study report of 20 patients who were diagnosed with Covid 19 and out of 20, 14 got negative reports on Day 6. The rest 6 patients were not considered in this report. (Source – https://www.forbes.com/sites/marybethpfeiffer/2020/03/22/one-patient-dodges-a-covid-bullet-is-she-a-harbinger-or-outlier/#2460233a5b84 )
One more case in New York for the 53 year old nurse who was diagnosed with Covid 19 as critical was given Plaquenil in her treatment. Before treatment she was having fever, feeling fatigue , coughing and a headache. However after having Plaquenil, she was responding to treatment. Her fever has gone now however she is still in the hospital for further treatment .
Another man in Florida who was on his deathbed due to the novel virus was saved using this anti-malarial drug. After a week treatment, doctors lost hope and asserted that they could nothing. The man was suffering from horrendous back pain, cough and fatigue. This man in fact bid goodbye to his family as he was hardly able to speak. Interestingly a friend of his sent him an article about anti malarial drug for treatment. The man insisted to doctors to provide this drug. After an hour of this drug, his heart was beating fast and within two hours he was not able to breathe. He was given Benadryl and other drugs and around 4.45 am he felt as if nothing has happened to him. The fever had gone and he can breathe it good. (source – https://nypost.com/2020/03/22/florida-man-with-coronavirus-says-drug-touted-by-trump-saved-his-life/ )
ICMR recommends Hydroxy-chloroquine too !!
Not only this, today the National Task Force for Covid19 constituted by ICMR recommends usage of HCQ (Hydroxychloroquine) drug for treatment of novel Sar2-Covid19 disease. (Source – https://www.thehindu.com/sci-tech/health/coronavirus-icmr-prescribes-anti-malarial-drug-for-high-risk-covid-19-cases/article31142391.ece )
Whether anti malarial vaccine would be effective against this virus is a matter of time. The French test report had a sample of small group of 20 people. Such a small sample cannot be a precedent for the whole world. The rush to put a drug for the vast majority of cases could also bring the risk too lives. Also providing such approved malarial drug to Covid19 patients may bring supplies issue for people with malarial disease.
The clinical studies of larger group needs to be conducted for the drug which prescribe its usage, dosage and duration. We just pray that the clinical tests for this vaccine comes positive against Coronavirus. Till that time stay safe and practice social distancing.
Disclaimer – The views and opinions expressed here is this blog is personal. Any similarity to any person or circumstances is purely incidental. The author does not advise usage or dosage of any medicine in the above column. It is advised not to take any of the medicines mentioned above. Any risk associated after taking above medicines without proper guidance and consultation rests with the person consuming the medicine.